Chris Janson, M.D. - MED - Neurosurgery Department, University of Minnesota

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	Home > Training Programs > Neurosurgery Residency Training > Current Residents > Chris Janson, M.D.

Chris Janson, M.D.

Dr. Christopher Janson

Dr. Janson completed his undergraduate degree at Stanford University, and his medical degree at Yale University. He is a past recipient of a Cambridge University, Trinity College Exchange Studentship, American Heart Association Predoctoral Research Fellowship, and an American Academy of Neurology Palatucci Advocacy Leadership Forum Award.

Dr. Janson served on the editorial board of the Yale Journal of Biology and Medicine, and currently serves on the editorial board of the journal Stem Cells and Development. His research interests are in the areas of gene therapy using viral based antisense, molecular genetics of Alzheimer’s disease, instrumentation for stereotaxic and functional neurosurgery, minimally invasive neurosurgery, and ethical issues in genetics and gene therapy.

Publications:

1) M. Assadi, P. Leone, J. J. Veloski, R. J. Schwartzman, C. G. Janson, and J. V. Campellone. Validating an Ataxia Functional Composite Scale in spinocerebellar ataxia. J.Neurol.Sci. 268 (1-2):136-139, 2008.
2) M. Assadi, J. V. Campellone, C. G. Janson, J. J. Veloski, R. J. Schwartzman, and P. Leone. Treatment of spinocerebellar ataxia with buspirone. J.Neurol.Sci. 260 (1-2):143-146, 2007.
3) C. G. Janson, S. W. McPhee, J. Francis, D. Shera, M. Assadi, A. Freese, P. Hurh, J. Haselgrove, D. J. Wang, L. Bilaniuk, and P. Leone. Natural history of Canavan disease revealed by proton magnetic resonance spectroscopy (1H-MRS) and diffusion-weighted MRI. Neuropediatrics 37 (4):209-221, 2006.
4) S. W. McPhee, C. G. Janson, C. Li, R. J. Samulski, A. S. Camp, J. Francis, D. Shera, L. Lioutermann, M. Feely, A. Freese, and P. Leone. Immune responses to AAV in a phase I study for Canavan disease. J.Gene Med. 8 (5):577-588, 2006.
5) C. G. Janson, E. H. Kolodny, B. J. Zeng, S. Raghavan, G. Pastores, P. Torres, M. Assadi, S. McPhee, O. Goldfarb, B. Saslow, A. Freese, D. J. Wang, L. Bilaniuk, D. Shera, and P. Leone. Mild-onset presentation of Canavan's disease associated with novel G212A point mutation in aspartoacylase gene. Ann.Neurol. 59 (2):428-431, 2006.
6) C. G. Janson, M. Assadi, J. Francis, L. Bilaniuk, D. Shera, and P. Leone. Lithium citrate for Canavan disease. Pediatr.Neurol. 33 (4):235-243, 2005.
7) B. Tavazzi, G. Lazzarino, P. Leone, A. M. Amorini, F. Bellia, C. G. Janson, Pietro Di, V, L. Ceccarelli, S. Donzelli, J. S. Francis, and B. Giardina. Simultaneous high performance liquid chromatographic separation of purines, pyrimidines, N-acetylated amino acids, and dicarboxylic acids for the chemical diagnosis of inborn errors of metabolism. Clin.Biochem. 38 (11):997-1008, 2005.
8) C. G. Janson. Essay: White daisies on my mind (Requiem for an Alzheimer patient). Neurology 65 (4):654-656, 2005.
9) S. W. McPhee, J. Francis, C. G. Janson, T. Serikawa, K. Hyland, E. O. Ong, S. S. Raghavan, A. Freese, and P. Leone. Effects of AAV-2-mediated aspartoacylase gene transfer in the tremor rat model of Canavan disease. Brain Res.Mol.Brain Res. 135 (1-2):112-121, 2005.
10) C. G. Janson. Stem cells: moving ahead on all fronts. J.Hematother.Stem Cell Res. 11 (2):159-160, 2002.
11) C. G. Janson, T. M. Ramesh, M. J. During, P. Leone, and J. Heywood. Human intrathecal transplantation of peripheral blood stem cells in amyotrophic lateral sclerosis. J.Hematother.Stem Cell Res. 10 (6):913-915, 2001.
12) C. G. Janson, Y. Chen, Y. Li, and D. Leifer. Functional regulatory regions of human transcription factor MEF2C. Brain Res.Mol.Brain Res. 97 (1):70-82, 2001.
13) C. G. Janson, S. W. McPhee, P. Leone, A. Freese, and M. J. During. Viral-based gene transfer to the mammalian CNS for functional genomic studies. Trends Neurosci. 24 (12):706-712, 2001.
14) P. Leone, C. G. Janson, S. J. McPhee, and M. J. During. Global CNS gene transfer for a childhood neurogenetic enzyme deficiency: Canavan disease. Curr.Opin.Mol.Ther. 1 (4):487-492, 1999.
15) C. G. Janson and M. J. During. Viral vectors as part of an integrated functional genomics program. Genomics 78 (1-2):3-6, 2001.
16) R. Xu, C. G. Janson, M. Mastakov, P. Lawlor, D. Young, A. Mouravlev, H. Fitzsimons, K. L. Choi, H. Ma, M. Dragunow, P. Leone, Q. Chen, B. Dicker, and M. J. During. Quantitative comparison of expression with adeno-associated virus (AAV-2) brain-specific gene cassettes. Gene Ther. 8 (17):1323-1332, 2001.
17) P. Leone, C. G. Janson, L. Bilaniuk, Z. Wang, F. Sorgi, L. Huang, R. Matalon, R. Kaul, Z. Zeng, A. Freese, S. W. McPhee, E. Mee, and M. J. During. Aspartoacylase gene transfer to the mammalian central nervous system with therapeutic implications for Canavan disease. Ann.Neurol. 48 (1):27-38, 2000.
18) P. Leone, S. W. McPhee, C. G. Janson, B. L. Davidson, A. Freese, and M. J. During. Multi-site partitioned delivery of human tyrosine hydroxylase gene with phenotypic recovery in Parkinsonian rats. Neuroreport 11 (6):1145-1151, 2000.
19) M. J. During and C. G. Janson. PNAs breach the blood-brain barrier? Nat.Biotechnol. 17 (8):753-754, 1999.
20) C. G. Janson. Thoughts on medical ethics and education. Pharos Alpha.Omega.Alpha.Honor.Med.Soc. 60 (4):31-34, 1997.

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